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For years, my future seemed pretty straightforward. At some point, I was going to need a knee replacement. I have bone-on-bone osteoarthritis in both knees. Every orthopedic appointment seemed to end with the same conversation. The surgery wasn't necessarily needed today, but it was coming eventually. The only question was when. To further complicate and concern my health, my mother passed away after her second knee replacement surgery. Blood clots entered her lungs the day a
What I found was both wild and well-documented: the gut—yes, your gut—may be deeply involved in how osteoarthritis develops and how it could be treated. A hormone called GLP-1, best known for regulating digestion and appetite, might also protect cartilage and reduce joint inflammation.
Researchers call it the gut-joint axis, and it’s changing the way we think about osteoarthritis.